SCHEMBL1402999

SCHEMBL1402999

CC(=O)C1=CSCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10984528 0.71 LMNA (0.34)
SCHEMBL10984532 0.71 LMNA (0.34)
SCHEMBL10920332 0.70 SRD5A2 (0.42)
SCHEMBL787457 0.67
SCHEMBL10296529 0.66
SCHEMBL2628905 0.65
SCHEMBL2130103 0.64
SCHEMBL116457 0.58
SCHEMBL17244089 0.57
SCHEMBL12588958 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148320-A1 Screw type processing device and product using the device UCHIYAMA KOSUKE 2007-06-28 US claimed
EP-1674502-A1 SCREW TYPE PROCESSING DEVICE AND PRODUCT USING THE DEVICE Uchiyama, Kosuke (JP) 2006-06-28 EP claimed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US disclosed
US-9057049-B2 Transgenic plants with reduced expression of AMADH2 and elevated levels of 2-acetyl-1-pyrroline KASETSART UNIVERSITY (TH) 2015-06-16 US disclosed
US-9005689-B2 Process for the preparation of a flavor active composition NESTEC S.A. (CH) 2015-04-14 US disclosed
US-9005689-B2 Process for the preparation of a flavor active composition NESTEC S.A. (CH) 2015-04-14 US disclosed
US-20120141643-A1 FLAVOUR ACTIVE COMPOSITION NESTEC S.A. (CH) 2012-06-07 US disclosed
US-20120141643-A1 FLAVOUR ACTIVE COMPOSITION NESTEC S.A. (CH) 2012-06-07 US disclosed
US-20110179518-A1 TRANSGENIC PLANTS WITH REDUCED EXPRESSION OF AMADH2 AND ELEVATED LEVELS OF 2-ACETYL-1-PYRROLINE NATIONAL SCIENCE & TECHNOLOGY DEVELOPMENT AGENCY (TH) 2011-07-21 US disclosed
EP-2292104-A1 A flavour active composition Nestec S.A. (CH) 2011-03-09 EP disclosed
US-20070148320-A1 Screw type processing device and product using the device UCHIYAMA KOSUKE 2007-06-28 US disclosed
EP-1674502-A1 SCREW TYPE PROCESSING DEVICE AND PRODUCT USING THE DEVICE Uchiyama, Kosuke (JP) 2006-06-28 EP disclosed