Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321675 | 1.00 | KMT2A (0.68) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL15797043 | 0.98 | KMT2A (0.70) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL6322623 | 0.94 | KMT2A (0.70) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL1963069 | 0.90 | — | — | |
| SCHEMBL9129119 | 0.82 | KMT2A (0.71) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL9129124 | 0.82 | KMT2A (0.71) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL9442180 | 0.82 | KMT2A (0.55) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL8410897 | 0.82 | EPHX1 (0.57) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL14654974 | 0.81 | KMT2A (0.69) | KMT2APOLBGAATDP1EPHX1 | |
| SCHEMBL22436470 | 0.81 | KMT2A (0.64) | KMT2APOLBGAATDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340708-A | ACRYLIC ESTERS AND A CYANO-ACETIC ACID, ESTOR OR AMIDE IS PRESSENT | HENKEL KOMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-07-20 | — | — | US | claimed |
| CN-118946553-A | SARM1 inhibitor compound, pharmaceutical composition comprising the same, and preparation method and use thereof | 深圳众格生物科技有限公司 | 2024-11-12 | — | — | CN | disclosed |
| WO-2023193809-A1 | SARM1 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PREPARATION METHOD THEREFOR AND USES THEREOF | 深圳众格生物科技有限公司 | 2023-10-12 | — | — | WO | disclosed |
| WO-2020249821-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-12-17 | — | — | WO | disclosed |
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | disclosed |
| US-8344016-B2 | Pyrazole derivatives as 11-beta-HSD1 inhibitors | ASTRAZENECA AB (SE) | 2013-01-01 | — | — | US | disclosed |
| US-8344016-B2 | Pyrazole derivatives as 11-beta-HSD1 inhibitors | ASTRAZENECA AB (SE) | 2013-01-01 | — | — | US | disclosed |
| US-8344016-B2 | Pyrazole derivatives as 11-beta-HSD1 inhibitors | ASTRAZENECA AB (SE) | 2013-01-01 | — | — | US | disclosed |
| WO-2012158843-A2 | KINASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-22 | — | — | WO | disclosed |
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4208324-A | Disperse diaminopyridine-3-azo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4172944-A | Water insoluble styryl dyestuffs having hetero-aryl methylene substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-10-30 | — | — | US | disclosed |
| US-4098598-A | PLANT GROWTH REGULATORS | HOFFMANN-LA ROCHE INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4066637-A | BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4028089-A | BENZOXAZOLINYLIDENE-MALONITRILE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1977-06-07 | — | — | US | disclosed |
| US-4016191-A | WATER INSOLUBLE; LIGHTFASTNESS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |