Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129119 | 1.00 | KMT2A (0.71) | KMT2AEPHX2POLBGAATDP1 | |
| SCHEMBL1963069 | 0.92 | — | — | |
| SCHEMBL15797043 | 0.84 | KMT2A (0.70) | KMT2AEPHX2POLBGAATDP1 | |
| SCHEMBL6322623 | 0.84 | KMT2A (0.70) | KMT2APOLBGAATDP1ALDH1A1 | |
| SCHEMBL14654974 | 0.83 | KMT2A (0.69) | KMT2APOLBGAATDP1ALDH1A1 | |
| SCHEMBL6321675 | 0.82 | KMT2A (0.68) | KMT2AEPHX2POLBGAATDP1 | |
| SCHEMBL1403047 | 0.82 | KMT2A (0.68) | KMT2AEPHX2POLBGAATDP1 | |
| SCHEMBL22436470 | 0.79 | KMT2A (0.64) | KMT2APOLBGAATDP1ALDH1A1 | |
| SCHEMBL14652034 | 0.79 | KMT2A (0.63) | KMT2APOLBGAATDP1ALDH1A1 | |
| SCHEMBL6324524 | 0.79 | KMT2A (0.63) | KMT2AEPHX2POLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |