⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129124 | 0.92 | KMT2A (0.71) | — | |
| SCHEMBL9129119 | 0.92 | KMT2A (0.71) | — | |
| SCHEMBL6322623 | 0.91 | KMT2A (0.70) | — | |
| SCHEMBL15797043 | 0.91 | KMT2A (0.70) | — | |
| SCHEMBL14654974 | 0.90 | KMT2A (0.69) | — | |
| SCHEMBL6321675 | 0.90 | KMT2A (0.68) | — | |
| SCHEMBL1403047 | 0.90 | KMT2A (0.68) | — | |
| SCHEMBL22436470 | 0.86 | KMT2A (0.64) | — | |
| SCHEMBL14652034 | 0.86 | KMT2A (0.63) | — | |
| SCHEMBL6324524 | 0.86 | KMT2A (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885337-B1 | FTO INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2025-01-15 | — | — | EP | disclosed |
| CN-118946553-A | SARM1 inhibitor compound, pharmaceutical composition comprising the same, and preparation method and use thereof | 深圳众格生物科技有限公司 | 2024-11-12 | — | — | CN | disclosed |
| WO-2023193809-A1 | SARM1 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PREPARATION METHOD THEREFOR AND USES THEREOF | 深圳众格生物科技有限公司 | 2023-10-12 | — | — | WO | disclosed |
| US-20230142913-A1 | TRICYCLIC HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | REPARE THERAPEUTICS INC. (CA) | 2023-05-11 | — | — | US | disclosed |
| CN-107922316-B | FTO inhibitors | 北京生命科学研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-113801187-A | Preparation and application of Michael acceptor type main protease inhibitor targeting novel coronavirus | 南开大学 | 2021-12-17 | — | — | CN | disclosed |
| EP-3885337-A1 | FTO INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3885337-A1 | FTO INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-09-29 | — | — | EP | disclosed |
| US-20210238127-A1 | FTO Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-08-05 | — | — | US | disclosed |
| US-20210238127-A1 | FTO Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-08-05 | — | — | US | disclosed |
| WO-2007073283-A1 | SUBSTITUTED CINNOLINE DERIVATIVES AS GABAA-RECEPTOR MODULATORS AND METHOD FOR THEIR SYNTHESIS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |
| US-20070142328-A1 | Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | US | disclosed |
| US-20070142382-A1 | Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | US | disclosed |
| US-20070049757-A1 | Methods for the synthesis of substituted amino uracils | ADENOSINE THERAPEUTICS, LLC | 2007-03-01 | — | — | US | disclosed |
| US-20070049757-A1 | Methods for the synthesis of substituted amino uracils | ADENOSINE THERAPEUTICS, LLC | 2007-03-01 | — | — | US | disclosed |
| US-20070049757-A1 | Methods for the synthesis of substituted amino uracils | ADENOSINE THERAPEUTICS, LLC | 2007-03-01 | — | — | US | disclosed |
| EP-1565461-A2 | ANTIBACTERIAL SUBSTITUTED CYANOMETHYL(ENE)PIPERIDINOPHENYL OXAZOLIDINONES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Patel, Mahesh V. (IN) | 2005-08-24 | — | — | EP | disclosed |
| US-20040063954-A1 | Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoprotein sites | WOCKHARDT LIMITED | 2004-04-01 | — | — | US | disclosed |
| WO-2004007489-A2 | ANTIBACTERIAL SUBSTITUTED CYANOMETHYL (ENE) PIPERIDINOPHENYL OXAZOLIDINONES, PROCESS OR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WOCKHARDT LIMITED (IN) | 2004-01-22 | — | — | WO | disclosed |
| US-4586954-A | Arylacryl aliphatic amide herbicidal compounds and methods of use | STAUFFER CHEMICAL CO. (US) | 1986-05-06 | — | — | US | disclosed |