Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 13/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031030 | 0.80 | IMPDH2 (0.50) | IMPDH2CYP1A2ALOX15MEN1CYP3A4 | |
| SCHEMBL1487601 | 0.76 | BRD4 (0.41) | IMPDH2CYP1A2MEN1CYP3A4CYP2D6 | |
| SCHEMBL13745858 | 0.74 | PTGER4 (0.34) | IMPDH2CYP1A2MEN1CYP3A4CYP2D6 | |
| SCHEMBL14031036 | 0.73 | IMPDH2 (0.46) | IMPDH2CYP1A2ALOX15MEN1CYP3A4 | |
| SCHEMBL8318457 | 0.73 | CDK8 (0.63) | IMPDH2LRRK2CHEK1CDK2 | |
| SCHEMBL14031044 | 0.72 | IMPDH2 (0.42) | IMPDH2CYP1A2ALOX15MEN1CYP3A4 | |
| SCHEMBL23928899 | 0.72 | HTT (0.45) | MEN1KMT2APTGER4ALDH1A1 | |
| SCHEMBL14031125 | 0.72 | BRD4 (0.47) | PTGER4LRRK2ALDH1A1 | |
| SCHEMBL23452230 | 0.72 | PTGER4 (0.43) | PTGER4LRRK2ALDH1A1 | |
| SCHEMBL31020829 | 0.72 | HTT (0.45) | MEN1KMT2APTGER4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432375-B2 | JNK inhibitors | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |