Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23812505 | 1.00 | CYP3A4 (0.36) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL25481224 | 0.90 | CYP3A4 (0.36) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL23812504 | 0.85 | CYP3A4 (0.34) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL21288020 | 0.85 | CYP3A4 (0.46) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL25484423 | 0.84 | — | — | |
| SCHEMBL21415409 | 0.83 | POLB (0.39) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL25487999 | 0.82 | CA1 (0.41) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL31319784 | 0.81 | LMNA (0.37) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL17640848 | 0.80 | LMNA (0.36) | CYP3A4MAPTCYP2C9CYP2C19CA1 | |
| SCHEMBL18461300 | 0.80 | LMNA (0.36) | CYP3A4MAPTCYP2C9CYP2C19CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174481-B2 | Targeting ligands | Arrowhead Pharmaceuticals, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
| US-20190256849-A1 | Targeting Ligands | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2019-08-22 | — | — | US | disclosed |
| US-20080269450-A1 | Endosomolytic Poly-Beta-Aminoester Polymers | ROCHE MADISON INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256849-A1 | Targeting Ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
| US-11174481-B2 | Targeting ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.