Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640848 | 0.97 | LMNA (0.36) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL18461300 | 0.97 | LMNA (0.36) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL21415409 | 0.83 | POLB (0.39) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL25487999 | 0.83 | CA1 (0.41) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL25481224 | 0.82 | CYP3A4 (0.36) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL19695709 | 0.82 | BDNF (0.38) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL23812505 | 0.81 | CYP3A4 (0.36) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL14031822 | 0.81 | CYP3A4 (0.36) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL20329185 | 0.81 | LMNA (0.34) | LMNAKMT2ACYP3A4MAPTCYP2C9 | |
| SCHEMBL21702711 | 0.81 | LMNA (0.39) | LMNAKMT2ACYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219561-A | Naphthamide 1H-indazole derivative and preparation and application thereof | 上海润石医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |