Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881770 | 0.91 | KMT2A (0.46) | KDM4EALDH1A1KMT2AMEN1THRB | |
| SCHEMBL68651 | 0.91 | KMT2A (0.46) | KDM4EALDH1A1KMT2AMEN1THRB | |
| SCHEMBL21274378 | 0.91 | KMT2A (0.46) | KDM4EALDH1A1KMT2AMEN1THRB | |
| Bromide SCHEMBL10788752 | 0.89 | KMT2A (0.45) | KDM4EALDH1A1KMT2AMEN1THRB | |
| SCHEMBL68168 | 0.89 | THRB (0.47) | ALDH1A1KMT2AMEN1THRBTSHR | |
| SCHEMBL235038 | 0.82 | THRB (0.50) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL12860038 | 0.82 | THRB (0.50) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL7750904 | 0.82 | THRB (0.53) | KDM4EALDH1A1KMT2AMEN1THRB | |
| SCHEMBL10349193 | 0.81 | TSHR (0.50) | KDM4EALDH1A1KMT2AMEN1THRB | |
| SCHEMBL12354542 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291422-B1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2015-10-21 | — | — | EP | disclosed |
| US-8664324-B2 | Pigment dispersants with modified copolymers | BASF SE (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20110144260-A1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2011-06-16 | — | — | US | disclosed |
| EP-2291422-A1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009156277-A1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
| US-6100312-A | A CURABLE QUATERNARY AMMONIUM ADDITION COPOLYMER WITH A DISPERSED FINE-GRAIN PIGMENT; STORAGE STABILITY; COLOR FILTER USED IN A LIQUID CRYSTAL DISPLAY ELEMENT | FUJI PHOTO CO., LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-5998091-A | COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |