Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113143 | 0.83 | PTGS2 (0.53) | PTGS2CCR2ENPP2 | |
| SCHEMBL17069275 | 0.82 | PTGS2 (0.52) | PTGS2ENPP2 | |
| SCHEMBL30395150 | 0.82 | PTGS2 (0.52) | PTGS2ENPP2 | |
| SCHEMBL8605270 | 0.82 | PTGS2 (0.52) | PTGS2ENPP2 | |
| SCHEMBL17069339 | 0.82 | PTGS2 (0.52) | PTGS2ENPP2 | |
| SCHEMBL14033381 | 0.80 | CA1 (0.61) | PTGS2ENPP2 | |
| SCHEMBL5811040 | 0.80 | PTGS2 (0.50) | PTGS2ENPP2 | |
| SCHEMBL14034059 | 0.79 | ALDH1A1 (0.48) | LMNATSHR | |
| SCHEMBL11820501 | 0.78 | TSHR (0.61) | LMNATSHR | |
| SCHEMBL23159235 | 0.77 | PTGS2 (0.47) | PTGS2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |