Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033761 | 0.83 | HCAR2 (0.50) | TSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1073352 | 0.81 | TRPV1 (0.49) | — | |
| SCHEMBL1073350 | 0.81 | TRPV1 (0.49) | — | |
| SCHEMBL1122130 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1HTTSMN1; SMN2TEAD3 | |
| SCHEMBL721275 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1HTTSMN1; SMN2TEAD3 | |
| SCHEMBL1572986 | 0.78 | ALDH1A1 (0.45) | TSHRALDH1A1HTTSMN1; SMN2TEAD3 | |
| SCHEMBL1572988 | 0.78 | ALDH1A1 (0.45) | TSHRALDH1A1HTTSMN1; SMN2TEAD3 | |
| SCHEMBL5599476 | 0.78 | ALDH1A1 (0.47) | TSHRALDH1A1TDP1BTN3A1SMN1; SMN2 | |
| SCHEMBL5599478 | 0.78 | ALDH1A1 (0.47) | TSHRALDH1A1TDP1BTN3A1SMN1; SMN2 | |
| SCHEMBL31597606 | 0.77 | ALDH1A1 (0.51) | TSHRALDH1A1TDP1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442712-B2 | isocyclopentafuran derivatives; cannabinoid receptor ligand; antiinflammatory, anticarcinogenic, antidiabetic agent; neurodegenerative and cardiovascular diseases | SCHERING CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |