SCHEMBL5599478

SCHEMBL5599478

CC(C=O)=CCCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TSHR P16473 1/20 0.47
GRIK1 P39086 1/20 0.45
GPR52 Q9Y2T5 5/20 0.43
FFAR1 O14842 1/20 0.42
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
BTN3A1 O00481 1/20 0.41
ATM Q13315 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
KEAP1 Q14145 1/20 0.41
TRPV1 Q8NER1 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599476 1.00 ALDH1A1 (0.47) ALDH1A1TSHRGRIK1GPR52FFAR1
SCHEMBL17732044 0.89 HDAC1 (0.44) ALDH1A1TSHRSMN1; SMN2
SCHEMBL22394385 0.80 TP53 (0.45) TSHRLMNA
SCHEMBL352445 0.80 ALDH1A1 (0.50) ALDH1A1TSHRFFAR1HPGDSMN1; SMN2
SCHEMBL7286537 0.80 ALDH1A1 (0.50) ALDH1A1TSHRFFAR1HPGDSMN1; SMN2
SCHEMBL105976 0.79 TRPV1 (0.51) ALDH1A1GRIK1GPR52HPGDSMN1; SMN2
SCHEMBL14033341 0.78 TSHR (0.44) ALDH1A1TSHRSMN1; SMN2BTN3A1TDP1
SCHEMBL197322 0.77 GRIK1 (0.53) ALDH1A1GRIK1GPR52HPGDSMN1; SMN2
SCHEMBL14308631 0.77 ALDH1A1 (0.47) ALDH1A1GRIK1GPR52HPGDSMN1; SMN2
SCHEMBL197321 0.77 GRIK1 (0.53) ALDH1A1GRIK1GPR52HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070072789-A1 2-Methyl-5-phenylpentanal used as a rose odoriferous substance SYMRISE GMBH & CO. KG (DE) 2007-03-29 US disclosed
EP-1631247-A1 2-METHYL-5-PHENYLPENTANAL USED AS ROSE ODORIFEROUS SUBSTANCE Symrise GmbH & Co. KG (DE) 2006-03-08 EP disclosed
WO-2004105724-A1 2-METHYL-5-PHENYLPENTANAL USED AS ROSE ODORIFEROUS SUBSTANCE SYMRISE GMBH & CO. KG (DE) 2004-12-09 WO disclosed
EP-0291849-B1 4-METHYL-4-PHENYL-PENTAN-1-ALS, THEIR PREPARATION AND APPLICATION AS AROMA CHEMICALS BASF Aktiengesellschaft (DE) 1991-10-16 EP disclosed
EP-0291849-A2 4-Methyl-4-phenyl-pentan-1-als, their preparation and application as aroma chemicals BASF Aktiengesellschaft (DE) 1988-11-23 EP disclosed