Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675415 | 1.00 | NFE2L2 (0.35) | NFE2L2NOS2HMGCRCYP3A4HDAC1 | |
| SCHEMBL14392589 | 0.76 | NFE2L2 (0.32) | NFE2L2 | |
| SCHEMBL20076508 | 0.76 | ESR1 (0.33) | NFE2L2HDAC1HDAC6ERN1 | |
| SCHEMBL14033478 | 0.76 | ERN1 (0.52) | NFE2L2HDAC1HDAC6ERN1 | |
| SCHEMBL25686111 | 0.74 | NFE2L2 (0.56) | NFE2L2HMGCRCYP3A4 | |
| SCHEMBL13535962 | 0.74 | NFE2L2 (0.56) | NFE2L2HMGCRCYP3A4 | |
| SCHEMBL18937938 | 0.74 | HMGCR (0.31) | HMGCRCYP3A4 | |
| SCHEMBL30668 | 0.72 | HDAC1 (0.48) | NFE2L2HDAC1HDAC6 | |
| SCHEMBL23134798 | 0.70 | TUBB1 (0.40) | NFE2L2CYP3A4HDAC1HDAC6 | |
| SCHEMBL21872444 | 0.70 | HMGCR (0.33) | HMGCRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435455-B2 | Dihydrocoumarin derivative, liquid crystal composition containing the same, and liquid crystal display device | CHISSO CORPORATION (JP) | 2008-10-14 | — | — | US | disclosed |