Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26577860 | 0.78 | ALDH1A1 (0.31) | ERN1 | |
| SCHEMBL20076626 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL14033478 | 0.77 | ERN1 (0.52) | NFE2L2HDAC1HDAC6ERN1 | |
| SCHEMBL1611521 | 0.76 | ESR1 (0.35) | ESR1ESR2ERN1TP53TDP1 | |
| SCHEMBL14033477 | 0.76 | NFE2L2 (0.35) | NFE2L2HDAC1HDAC6ERN1 | |
| SCHEMBL21675415 | 0.76 | NFE2L2 (0.35) | NFE2L2HDAC1HDAC6ERN1 | |
| SCHEMBL4537972 | 0.74 | — | — | |
| SCHEMBL2485696 | 0.74 | — | — | |
| SCHEMBL30668 | 0.74 | HDAC1 (0.48) | NFE2L2HDAC1HDAC6 | |
| SCHEMBL13451736 | 0.74 | TRPV4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |