Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13307944 | 0.89 | MEN1 (0.53) | OPRD1OPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL13304693 | 0.85 | KCNH2 (0.52) | OPRD1OPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL14034016 | 0.79 | MEN1 (0.49) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL14034022 | 0.79 | CYP2D6 (0.55) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL14033816 | 0.79 | CYP2D6 (0.55) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL14033487 | 0.79 | HRH3 (0.44) | OPRD1OPRM1OPRK1OPRL1MEN1 | |
| Hydrochloric Acid SCHEMBL6797327 | 0.76 | OPRD1 (0.97) | OPRD1OPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL4146000 | 0.73 | MEN1 (0.58) | OPRD1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL2537196 | 0.73 | MEN1 (0.58) | OPRD1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL2315253 | 0.73 | MEN1 (0.58) | OPRD1OPRM1OPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |