Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.81 |
| ▸ | MIF | P14174 | 8/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 3/20 | 0.72 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | CASP3 | P42574 | 3/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679848 | 0.90 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL29546151 | 0.90 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL980327 | 0.90 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL820654 | 0.90 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL29546087 | 0.90 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL15153677 | 0.90 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL8543003 | 0.87 | MAOB (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL8548101 | 0.87 | MAOB (0.77) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL21169395 | 0.87 | MIF (1.00) | MAOBMIFCYP19A1PKMCYP11B2 | |
| SCHEMBL8548104 | 0.87 | MAOB (0.77) | MAOBMIFCYP19A1PKMCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |