SCHEMBL29546151

SCHEMBL29546151

O=C1C(=Cc2ccccc2)CCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 1.00
MIF P14174 9/20 0.81
MAPT P10636 4/20 0.81
CYP19A1 P11511 3/20 0.77
PKM P14618 2/20 0.77
CYP11B2 P19099 1/20 0.77
MAPK1 P28482 1/20 0.77
MAOA P21397 1/20 0.72
ALDH1A1 P00352 1/20 0.70
KMT2A Q03164 1/20 0.70
CYP1A2 P05177 1/20 0.69
CASP3 P42574 2/20 0.68
RAB9A P51151 2/20 0.68
SENP8 Q96LD8 2/20 0.68
SENP7 Q9BQF6 2/20 0.68
SENP6 Q9GZR1 2/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
KDM4E B2RXH2 1/20 0.65
NPC1 O15118 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15153677 1.00 MAOB (1.00) MAOBMIFMAPTCYP19A1PKM
SCHEMBL29546087 1.00 MAOB (1.00) MAOBMIFMAPTCYP19A1PKM
SCHEMBL980327 1.00 MAOB (1.00) MAOBMIFMAPTCYP19A1PKM
SCHEMBL29679848 1.00 MAOB (1.00) MAOBMIFMAPTCYP19A1PKM
SCHEMBL820654 1.00 MAOB (1.00) MAOBMIFMAPTCYP19A1PKM
SCHEMBL6958006 0.90 MIF (1.00) MAOBMIFMAPTCYP19A1PKM
SCHEMBL13203410 0.90 MAOB (0.81) MAOBMIFMAPTCYP19A1PKM
SCHEMBL14033869 0.90 MAOB (0.81) MAOBMIFMAPTCYP19A1PKM
SCHEMBL8548101 0.87 MAOB (0.77) MAOBMIFMAPTCYP19A1PKM
SCHEMBL6825622 0.87 CYP19A1 (1.00) MAOBMIFMAPTCYP19A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230457-A 2-benzylidene tetralone derivatives and preparation method and application thereof 中山大学 2022-03-25 CN claimed
US-20250374828-A1 ORGANIC COMPOUND SEMICONDUCTOR ENERGY LAB (JP) 2025-12-04 US disclosed
US-20250331420-A1 Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-10-23 US disclosed
EP-3709966-B1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT OREAL (FR) 2024-12-11 EP disclosed
CN-115925530-B 3, 4-dihydronaphthalene-1 (2H) -one compound, preparation method and application 滨州医学院 2024-03-12 CN disclosed
CN-115925530-A 3,4-dihydronaphthalene-1 (2H) -ketone compound, preparation method and application 滨州医学院 2023-04-07 CN disclosed
CN-114230457-A 2-benzylidene tetralone derivatives and preparation method and application thereof 中山大学 2022-03-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250374828-A1 ORGANIC COMPOUND SUN2, ORC3, EML4 MAOB 663/4885MIF 3343/4885MAPT 1469/4885
US-20250331420-A1 Organic Compound CRY1, CYP1A1, OXER1 MAOB 1176/4885MIF 3123/4885MAPT 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.