Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 11/20 | 0.47 |
| ▸ | F10 | P00742 | 10/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034063 | 1.00 | AKR1C3 (0.65) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL3437912 | 0.91 | ALDH1A1 (0.73) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL3437914 | 0.91 | ALDH1A1 (0.73) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL29019998 | 0.88 | MAPT (0.57) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL29019996 | 0.88 | MAPT (0.57) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL176860 | 0.85 | HSD11B1 (0.68) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL176859 | 0.85 | HSD11B1 (0.68) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL394499 | 0.85 | HSD11B1 (0.68) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL394500 | 0.85 | HSD11B1 (0.68) | AKR1C3AKR1C1NPC1MAPTHPGD | |
| SCHEMBL8882867 | 0.85 | AKR1C3 (0.89) | AKR1C3AKR1C1NPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |