Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051746 | 0.88 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11258552 | 0.74 | ALDH1A1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9390487 | 0.74 | ALDH1A1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22699174 | 0.74 | ALDH1A1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13447136 | 0.71 | HPGD (0.33) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3438117 | 0.69 | CYP1A2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3438119 | 0.69 | CYP1A2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8283668 | 0.69 | CYP2C9 (0.59) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11290392 | 0.69 | MEN1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11290388 | 0.69 | MEN1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |