SCHEMBL14034342

SCHEMBL14034342

C/C1=C/C/C(C(C)C)=C/CC(C)(O)C(O)CC/C(C)=C/CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.47
MET P08581 2/20 0.41
PTPN1 P18031 2/20 0.41
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CNR2 P34972 1/20 0.36
PPARA Q07869 1/20 0.36
TAS2R46 P59540 4/20 0.31
PTAFR P25105 1/20 0.31
RECQL P46063 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TERT O14746 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14034314 0.77 STAT3 (0.44) STAT3METMEN1KMT2APTAFR
SCHEMBL3680738 0.72 STAT3 (0.46) STAT3METPTPN1MEN1KMT2A
SCHEMBL3680737 0.72 STAT3 (0.46) STAT3METPTPN1MEN1KMT2A
SCHEMBL12697928 0.70 HSD11B1 (0.31)
SCHEMBL3675688 0.66 STAT3 (0.40) STAT3METPTPN1MEN1KMT2A
SCHEMBL3675691 0.66 STAT3 (0.40) STAT3METPTPN1MEN1KMT2A
Incensole SCHEMBL29369781 0.64 STAT3 (1.00) STAT3METMEN1KMT2ACNR2
Incensole SCHEMBL13394034 0.64 STAT3 (1.00) STAT3METMEN1KMT2ACNR2
Incensole SCHEMBL20565148 0.64 STAT3 (1.00) STAT3METMEN1KMT2ACNR2
Incensole SCHEMBL20565149 0.64 STAT3 (1.00) STAT3METMEN1KMT2ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080275117-A1 Compositions and Methods Comprising Boswellia Species HERBALSCIENCE SINGAPORE PTE. LTD. (SG) 2008-11-06 US disclosed