Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6128867 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14038149 | 0.85 | PPM1B (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12992688 | 0.85 | PPM1B (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14137635 | 0.85 | PPM1B (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10050521 | 0.84 | PPM1B (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14189734 | 0.84 | PPM1B (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9605862 | 0.84 | PPM1B (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8400471 | 0.84 | PPM1B (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14189733 | 0.84 | PPM1B (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8817477 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080292588-A1 | 1-METHYL-BENZO[1,2,4]THIADIAZINE 1-OXIDE DERIVATIVES | ANADYS PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292588-A1 | 1-METHYL-BENZO[1,2,4]THIADIAZINE 1-OXIDE DERIVATIVES | CYP1B1, CYP2E1, DAZAP1 | MEN1 3139/4885KMT2A 1229/4885ALDH1A1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.