Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14137635 | 1.00 | PPM1B (0.41) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL12992688 | 1.00 | PPM1B (0.41) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL9605862 | 0.86 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL14189733 | 0.86 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL10050521 | 0.86 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL8400471 | 0.86 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL14189734 | 0.86 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL6128867 | 0.85 | MEN1 (0.43) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL14034644 | 0.85 | MEN1 (0.43) | PPM1BPTPN1PPP1CCALDH1A1MEN1 | |
| SCHEMBL392906 | 0.81 | ALDH1A1 (0.40) | PPM1BPTPN1PPP1CCALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144500-A2 | 1-METHYL-BENZO[1,2,4]THIADIAZINE, 1-OXIDE DERIVATIVES | ANADYS PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |