SCHEMBL14035191

SCHEMBL14035191

Cc1cc(C)c(CCC2CCC(C3CCCCC3)CC2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.35
ALOX5 P09917 1/20 0.35
OPRL1 P41146 3/20 0.34
DAO P14920 2/20 0.33
EPHX2 P34913 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
TAS1R2 Q8TE23 2/20 0.31
RORC P51449 4/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12433696 0.89 HRH3 (0.33) HRH3
SCHEMBL14035414 0.84 HRH3 (0.38) HRH3
SCHEMBL12433605 0.80 SIRT2 (0.36) HRH3CYP3A4
SCHEMBL12769386 0.77 PKM (0.33) CYP3A4
SCHEMBL21648929 0.75 HRH3 (0.31) HRH3DAO
SCHEMBL11933091 0.74 SLC6A2 (0.44) OPRL1DAO
SCHEMBL18464122 0.74 DAO (0.37) ALOX5OPRL1DAO
SCHEMBL8767216 0.72 ALOX5 (0.37) ALOX5OPRL1DAO
SCHEMBL23520435 0.70
SCHEMBL26802905 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655360-B1 Compound having alkyl on benzene ring, liquid crystal compositions having the compound and liquid crystal display device having the liquid crystal composition CHISSO CORP (JP) 2008-11-12 EP disclosed