SCHEMBL14035565

SCHEMBL14035565

Cc1ccc(NC(=O)CC(OC(C)(C)C(=O)C(C)OC(C)(C)C)C(=O)C(C)(C)C)c(S(=O)(=O)O)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
GAA P10253 3/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 2/20 0.34
HTT P42858 2/20 0.33
BRD4 O60885 1/20 0.33
MAPT P10636 3/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LPAR1 Q92633 2/20 0.32
POLB P06746 2/20 0.32
KDM4E B2RXH2 1/20 0.32
RECQL P46063 1/20 0.32
CASP6 P55212 1/20 0.32
ELAVL1 Q15717 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PPARA Q07869 2/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13767940 0.90 KMT2A (0.35) KMT2AGAALMNAMEN1HTT
SCHEMBL13844226 0.86 KMT2A (0.33) KMT2AGAALMNAMEN1HTT
SCHEMBL13844133 0.79 ALDH1A1 (0.36) LMNAHTTMAPTALDH1A1L3MBTL1
SCHEMBL13768015 0.77 CA1 (0.37) GAAHTTHSD17B10ALDH1A1SMN1; SMN2
SCHEMBL12141395 0.73 HTT (0.36) KMT2AGAALMNAMEN1HTT
SCHEMBL13767997 0.71 CD40 (0.39)
SCHEMBL12960523 0.70 L3MBTL1 (0.51) KMT2AGAALMNAMEN1HTT
SCHEMBL13768116 0.70 CYP1A2 (0.33) GAALMNAALDH1A1L3MBTL1
SCHEMBL14035564 0.69 CA1 (0.39) LMNAMAPTALDH1A1SMN1; SMN2POLB
SCHEMBL7527649 0.69 KMT2A (0.53) KMT2AGAALMNAMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1774410-B1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KK (JP) 2008-11-19 EP disclosed