Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446905 | 0.79 | ALDH1A1 (0.49) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL8446966 | 0.77 | ALDH1A1 (0.52) | MMP3BCL2L1KDM4EKMT2AALDH1A1 | |
| SCHEMBL8443800 | 0.75 | ALDH1A1 (0.45) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL8446328 | 0.74 | EPHX2 (0.57) | HPGDLMNARAB9AMAPK1NPC1 | |
| SCHEMBL8446811 | 0.73 | NPC1 (0.48) | HPGDBACE1RAB9ANPC1GAA | |
| SCHEMBL4476506 | 0.71 | KDM4E (0.63) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| Acetaldehyde SCHEMBL9812963 | 0.69 | MMP3 (0.71) | MMP3BCL2L1KMT2AMEN1MAPT | |
| SCHEMBL6279507 | 0.68 | MMP3 (0.46) | MMP3BCL2L1KDM4EKMT2AALDH1A1 | |
| SCHEMBL7865208 | 0.67 | MMP3 (1.00) | MMP3BCL2L1KMT2AALDH1A1MEN1 | |
| SCHEMBL38273 | 0.67 | MMP3 (1.00) | MMP3BCL2L1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287424-A1 | AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS | WYETH (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287424-A1 | AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS | BACE1, BACE2, APP | MMP3 433/4885BCL2L1 368/4885KDM4E 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.