SCHEMBL14035728

SCHEMBL14035728

CC(C)c1ccc(C23CC4CC(CC(COC(=O)C(F)(F)OOS)(C4)C2)C3)cc1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
ALDH1A1 P00352 1/20 0.40
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
HTT P42858 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.37
SPHK2 Q9NRA0 1/20 0.35
RAD52 P43351 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14035706 0.89 KMT2A (0.49) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL14035731 0.88 MEN1 (0.42) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL14035716 0.87 HSD11B1 (0.44) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL14035718 0.87 MEN1 (0.39) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL685216 0.87 MEN1 (0.46) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL14035710 0.86 MEN1 (0.38) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL14035712 0.84 MEN1 (0.37) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL686238 0.83 LMNA (0.41) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL14009386 0.83 LMNA (0.40) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL2603085 0.81 LMNA (0.39) LMNAALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274426-A1 Using acrylic ester and sulfonium said salt; high resolution semiconductors; microfabrication patterns; excimer laser lithography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed