Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14709470 | 0.86 | HRH3 (0.51) | HRH3CYP2A13SMN1; SMN2HSD17B10HTT | |
| SCHEMBL16883444 | 0.83 | HRH3 (0.59) | HRH3CYP2A13SMN1; SMN2HTTNCF1 | |
| SCHEMBL14035671 | 0.83 | LMNA (0.51) | NCF1NPC1TP53RAB9AHPGD | |
| SCHEMBL14615359 | 0.82 | HRH3 (0.50) | HRH3CYP2A13SMN1; SMN2HSD17B10HTT | |
| SCHEMBL19266133 | 0.81 | CXCR4 (0.50) | HRH3MEN1KMT2ALMNATNKS | |
| SCHEMBL14872333 | 0.79 | HRH3 (0.59) | HRH3CYP2A13SMN1; SMN2HTTNCF1 | |
| SCHEMBL321512 | 0.79 | HRH3 (0.54) | HRH3CYP2A13SMN1; SMN2HSD17B10HTT | |
| SCHEMBL4974297 | 0.79 | HTT (0.55) | HRH3CYP2A13SMN1; SMN2HTTNCF1 | |
| SCHEMBL17724130 | 0.79 | HRH3 (0.54) | HRH3CYP2A13SMN1; SMN2HTTNCF1 | |
| SCHEMBL13161945 | 0.79 | HRH3 (0.62) | HRH3CYP2A13SMN1; SMN2HTTNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |