Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035869 | 0.82 | HRH3 (0.53) | HRH3MAPTSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL13061370 | 0.79 | HRH3 (0.67) | HRH3KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL20195827 | 0.78 | LMNA (0.49) | KDM4EHPGDNPC1TP53RAB9A | |
| SCHEMBL10397056 | 0.77 | HTT (0.52) | HRH3KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL10244180 | 0.77 | NCF1 (0.67) | HRH3KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL4106074 | 0.76 | CYP2A13 (0.65) | KDM4EMAPTHPGDHSD17B10MEN1 | |
| SCHEMBL27594166 | 0.76 | HPGD (0.51) | HRH3KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL27705945 | 0.76 | SMN1; SMN2 (0.51) | HRH3KDM4EMAPTSMN1; SMN2HPGD | |
| SCHEMBL301839 | 0.76 | HRH3 (0.71) | HRH3MAPTSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL25629312 | 0.74 | ALDH1A1 (0.39) | HRH3KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757584-A1 | Heterocyclic substituted amides, their production and their use | Abbott GmbH & Co. KG (DE) | 2007-02-28 | — | — | EP | disclosed |