Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242855 | 0.85 | PPARG (0.60) | GRM2PPARGPPARDPPARAMCL1 | |
| SCHEMBL26027547 | 0.72 | ACACB (0.61) | AOC3LMNATSHRNFKB1RAB9A | |
| SCHEMBL30669691 | 0.71 | HTR2C (0.57) | — | |
| SCHEMBL29138510 | 0.71 | HTR2C (0.57) | — | |
| SCHEMBL13699229 | 0.71 | PPARD (0.48) | GRM2PPARGPPARDPPARAMCL1 | |
| SCHEMBL7294501 | 0.70 | ACACB (0.69) | AOC3LMNATSHRNFKB1RAB9A | |
| SCHEMBL9522122 | 0.67 | AOC3 (0.50) | AOC3LMNATSHRNFKB1RAB9A | |
| SCHEMBL7979642 | 0.67 | CXCR1 (0.55) | AOC3RAB9ANR1I2CXCR1 | |
| SCHEMBL12621106 | 0.67 | PPARG (0.51) | PPARGPPARDPPARA | |
| SCHEMBL26022112 | 0.67 | AOC3 (0.52) | AOC3LMNATSHRNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |