Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 6/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979630 | 0.83 | HRH2 (0.62) | CXCR1HRH3HRH2HRH1 | |
| SCHEMBL7243866 | 0.83 | HRH2 (0.62) | CXCR1HRH3HRH2HRH1 | |
| SCHEMBL7245509 | 0.80 | CXCR1 (0.58) | CXCR1AOC3HRH3KCNH2HRH2 | |
| SCHEMBL7979690 | 0.79 | ATM (0.53) | HRH3KCNH2HRH2HRH1RAB9A | |
| SCHEMBL7254923 | 0.77 | GPR119 (0.57) | CXCR1HRH3HRH2HRH1 | |
| SCHEMBL7245375 | 0.77 | HRH3 (0.58) | HRH3HRH2HRH1 | |
| SCHEMBL26027547 | 0.74 | ACACB (0.61) | AOC3RAB9ANPC1NR1I2 | |
| SCHEMBL7301302 | 0.73 | CXCR1 (0.69) | CXCR1HRH3RAB9ANPC1MAPK1 | |
| SCHEMBL7294501 | 0.71 | ACACB (0.69) | AOC3RAB9ANPC1CA12CA1 | |
| SCHEMBL26022112 | 0.71 | AOC3 (0.52) | CXCR1AOC3RAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |