Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | CSK | P41240 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456271 | 0.87 | SLC7A5 (0.59) | TPH1ANPEPENPEPSLC7A5ALPI | |
| SCHEMBL456272 | 0.87 | SLC7A5 (0.59) | TPH1ANPEPENPEPSLC7A5ALPI | |
| SCHEMBL15081046 | 0.81 | ALDH1A1 (0.47) | TPH1ANPEPENPEPSLC7A5ERAP2 | |
| SCHEMBL12673428 | 0.81 | ALDH1A1 (0.47) | TPH1ANPEPENPEPSLC7A5ERAP2 | |
| SCHEMBL13594791 | 0.78 | EPHX2 (0.46) | TPH1PTGS1MEN1NPC1RAB9A | |
| SCHEMBL2003577 | 0.75 | KMT2A (0.52) | HIF1AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8237014 | 0.74 | SLC7A5 (0.56) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL12142792 | 0.74 | SLC7A5 (0.54) | TPH1ANPEPENPEPSLC7A5ALPI | |
| SCHEMBL8229295 | 0.74 | SLC7A5 (0.54) | TPH1ANPEPENPEPSLC7A5ALPI | |
| SCHEMBL12028774 | 0.74 | SLC7A5 (0.54) | TPH1ANPEPENPEPSLC7A5ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137471-A2 | MODIFIED INTERFERON BETA POLYPEPTIDES AND THEIR USES | AMBRX, INC. (US) | 2008-11-13 | — | — | WO | disclosed |