Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336909 | 0.83 | KMT2A (0.61) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL17892008 | 0.82 | TSHR (0.67) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL17892011 | 0.82 | TSHR (0.67) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL28757728 | 0.81 | PKM (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL21057140 | 0.81 | TSHR (0.49) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL2099802 | 0.81 | TSHR (0.69) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL21057142 | 0.81 | TSHR (0.49) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL3345930 | 0.81 | TSHR (0.69) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL12667905 | 0.81 | TSHR (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL2112936 | 0.81 | PKM (0.54) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145007-B1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| WO-2008141154-A2 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2008-11-20 | — | — | WO | disclosed |