SCHEMBL21057142

SCHEMBL21057142

CC(Oc1ccc(Br)cc1I)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
KMT2A Q03164 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
LDHA P00338 1/20 0.42
PTGDR2 Q9Y5Y4 4/20 0.41
PTGDR Q13258 1/20 0.41
MEN1 O00255 1/20 0.40
HSD11B1 P28845 1/20 0.40
CYP1A2 P05177 1/20 0.39
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21057140 1.00 TSHR (0.49) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL21057170 0.84 LDHA (0.40) TSHRKMT2ASMN1; SMN2LMNAATM
SCHEMBL21059512 0.84 LMNA (0.44) TSHRKMT2ASMN1; SMN2LMNAATM
SCHEMBL21057167 0.84 LDHA (0.40) TSHRKMT2ASMN1; SMN2LMNAATM
SCHEMBL21059511 0.84 LMNA (0.44) TSHRKMT2ASMN1; SMN2LMNAATM
SCHEMBL21057246 0.83 SMN1; SMN2 (0.58) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL7826588 0.83 SMN1; SMN2 (0.58) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL23368020 0.82 TSHR (0.67) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL18331136 0.82 TSHR (0.50) TSHRHTR2AHTR2CHTR2BKMT2A
SCHEMBL3602820 0.82 TSHR (0.50) TSHRHTR2AHTR2CHTR2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP claimed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN claimed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO claimed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US claimed
EP-3723745-B1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-06-19 EP disclosed
CN-111491628-B Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2023-10-13 CN disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11591284-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-02-28 US disclosed
US-11147788-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2021-10-19 US disclosed
CN-111491628-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-04 CN disclosed
WO-2019115780-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US disclosed
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS (DK) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 TSHR 3626/4885HTR2A 3861/4885HTR2C 4504/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 TSHR 3626/4885HTR2A 3861/4885HTR2C 4504/4885
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders CPT1B, CLCN2, CACNB1 TSHR 3912/4885HTR2A 3420/4885HTR2C 3861/4885
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 TSHR 3626/4885HTR2A 3861/4885HTR2C 4504/4885
US-11147788-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 TSHR 3626/4885HTR2A 3861/4885HTR2C 4504/4885
US-11591284-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, CACNA1S TSHR 4324/4885HTR2A 3734/4885HTR2C 4093/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 TSHR 3626/4885HTR2A 3861/4885HTR2C 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.