Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616994 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL9616992 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL696157 | 0.71 | MEN1 (0.64) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL1678515 | 0.70 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8317756 | 0.70 | ALDH1A1 (0.81) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL57079 | 0.69 | ALDH1A1 (0.86) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10447200 | 0.69 | POLB (0.67) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL23124935 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL19650826 | 0.68 | KMT2A (0.57) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL13132353 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |