Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616994 | 1.00 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL14036684 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL8317756 | 0.76 | ALDH1A1 (0.81) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL1678515 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10447200 | 0.75 | POLB (0.67) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL14008435 | 0.74 | KDM4E (0.58) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL696157 | 0.74 | MEN1 (0.64) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4445449 | 0.73 | POLB (0.60) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9353086 | 0.72 | LMNA (0.59) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL57079 | 0.72 | ALDH1A1 (0.86) | ALDH1A1KDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4005265-A | — | — | None | — | — | JP | disclosed |
| JP-H045265-A | BENZYLAMINOCYCLOHEXANOL DERIVATIVE AND INTERMEDIATE THEREOF | YAMANOUCHI PHARMACEUT CO LTD | 1992-01-09 | — | — | JP | disclosed |