Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 5/20 | 0.38 |
| ▸ | ITPR2 | Q14571 | 2/20 | 0.38 |
| ▸ | ITPR1 | Q14643 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812221 | 0.97 | ITPR3 (0.36) | ITPR3ITPR2ITPR1 | |
| SCHEMBL1554143 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL8644323 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL933668 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL8932121 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL2936710 | 0.79 | CA1 (0.31) | — | |
| Water SCHEMBL16551673 | 0.76 | — | — | |
| SCHEMBL12858898 | 0.73 | ITPR3 (0.36) | ITPR3ITPR2ITPR1 | |
| SCHEMBL9551236 | 0.73 | ITPR3 (0.36) | ITPR3ITPR2ITPR1 | |
| SCHEMBL9551238 | 0.73 | ITPR3 (0.36) | ITPR3ITPR2ITPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212541-A1 | COMPOSITIONS AND METHODS TO PROTECT CELLS BY BLOCKING ENTRY OF PATHOGEN PROTEINS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-09-01 | — | — | US | claimed |
| WO-2011060144-A2 | COMPOSITIONS AND METHODS TO PROTECT CELLS BY BLOCKING ENTRY OF PATHOGEN PROTEINS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-05-19 | — | — | WO | claimed |
| EP-2291188-A2 | COMPOSITIONS AND METHODS TO PROTECT CELLS BY BLOCKING ENTRY OF PATHOGEN PROTEINS | Virginia Tech Intellectual Properties, Inc. (US) | 2011-03-09 | — | — | EP | claimed |
| US-20100093601-A1 | COMPOSITIONS AND METHODS TO PROTECT CELLS BY BLOCKING ENTRY OF PATHOGEN PROTEINS | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2010-04-15 | — | — | US | claimed |
| WO-2009143133-A2 | COMPOSITIONS AND METHODS TO PROTECT CELLS BY BLOCKING ENTRY OF PATHOGEN PROTEINS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2009-11-26 | — | — | WO | claimed |