SCHEMBL8932121

SCHEMBL8932121

O=C(O)O[C@H]1[C@H](OC(=O)O)[C@H](OC(=O)O)[C@H]1OC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8644323 1.00 CA1 (0.31) CA1CA2CA9
SCHEMBL1554143 1.00 CA1 (0.31) CA1CA2CA9
SCHEMBL933668 1.00 CA1 (0.31) CA1CA2CA9
SCHEMBL2936710 1.00 CA1 (0.31) CA1CA2CA9
Water SCHEMBL16551673 0.96
SCHEMBL1403670 0.79 ITPR3 (0.38)
SCHEMBL6061620 0.79
SCHEMBL5076651 0.77 POLB (0.33)
SCHEMBL2812221 0.77 ITPR3 (0.36)
SCHEMBL15520114 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1813592-B1 CAGE-SHAPED CYCLOBUTANOIC DIANHYDRIDES AND PROCESS FOR PRODUCTION THEREOF NISSAN CHEMICAL IND LTD (JP) 2012-10-10 EP claimed
EP-0573848-B1 Bile-acid derivatives, a process for their production and their use as medicines HOECHST AG (DE) 1997-12-03 EP disclosed
EP-0573848-A2 Bile-acid derivatives, a process for their production and their use as medicines HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-15 EP disclosed