Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010468 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL12151564 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1TSHRTDP1 | |
| SCHEMBL13530756 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1TSHRTDP1 | |
| SCHEMBL12154717 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1TSHRTDP1 | |
| SCHEMBL16576319 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL20557340 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL21418918 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL14010467 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL14036875 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL14010442 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |