Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811210 | 0.86 | MAPT (0.47) | MAPTCHRM5CHRM3SIGMAR1ANPEP | |
| SCHEMBL16800520 | 0.86 | MAPT (0.47) | MAPTCHRM5CHRM3SIGMAR1ANPEP | |
| SCHEMBL14259327 | 0.84 | CHRM5 (0.38) | CHRM5CHRM3MEN1KMT2ASIGMAR1 | |
| SCHEMBL10284050 | 0.80 | HSD17B10 (0.44) | HSD17B10 | |
| SCHEMBL27329590 | 0.77 | HSD17B10 (0.47) | MAPTMEN1KMT2AANPEPERAP2 | |
| SCHEMBL7039511 | 0.77 | HSD17B10 (0.47) | MAPTMEN1KMT2AANPEPERAP2 | |
| SCHEMBL5059158 | 0.77 | HSD17B10 (0.47) | MAPTMEN1KMT2AANPEPERAP2 | |
| SCHEMBL6424182 | 0.77 | HSD17B10 (0.47) | MAPTMEN1KMT2AANPEPERAP2 | |
| SCHEMBL3974583 | 0.77 | HSD17B10 (0.47) | MAPTMEN1KMT2AANPEPERAP2 | |
| SCHEMBL336114 | 0.75 | MAPT (0.49) | MAPTCHRM5CHRM3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144728-A1 | CONJUGATES WHICH BIND A BLOOD PROTEIN SUCH AS HUMAN SERUM ALBUMIN AND METHODS OF USING THE SAME IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING S.P.A. (IT) | 2008-11-27 | — | — | WO | disclosed |