Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811210 | 1.00 | MAPT (0.47) | MAPTCHRM5CHRM3HSD17B10ANPEP | |
| SCHEMBL7039511 | 0.89 | HSD17B10 (0.47) | MAPTHSD17B10ANPEPERAP2LMNA | |
| SCHEMBL6424182 | 0.89 | HSD17B10 (0.47) | MAPTHSD17B10ANPEPERAP2LMNA | |
| SCHEMBL27329590 | 0.89 | HSD17B10 (0.47) | MAPTHSD17B10ANPEPERAP2LMNA | |
| SCHEMBL3974583 | 0.89 | HSD17B10 (0.47) | MAPTHSD17B10ANPEPERAP2LMNA | |
| SCHEMBL5059158 | 0.89 | HSD17B10 (0.47) | MAPTHSD17B10ANPEPERAP2LMNA | |
| SCHEMBL472195 | 0.87 | MAPT (0.49) | MAPTCHRM5CHRM3HSD17B10ANPEP | |
| SCHEMBL336114 | 0.87 | MAPT (0.49) | MAPTCHRM5CHRM3HSD17B10ANPEP | |
| SCHEMBL14037201 | 0.86 | MAPT (0.38) | MAPTCHRM5CHRM3HSD17B10ANPEP | |
| SCHEMBL7453394 | 0.85 | MAPT (0.50) | MAPTCHRM5CHRM3HSD17B10ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015085005-A1 | MOLECULAR IMAGING PROBES | THE GENERAL HOSPITAL CORPORATION (US) | 2015-06-11 | — | — | WO | disclosed |