SCHEMBL136591

SCHEMBL136591

C=C(C)C(=O)OCCCCC(C)(C)O[SiH3]

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
THRB P10828 1/20 0.44
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16207848 0.98 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16286674 0.98 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL147606 0.97 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL24519228 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL81164 0.89 THRB (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19019780 0.86 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6829110 0.85 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19019783 0.85 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17077906 0.84 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL21555723 0.83 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MAT CO LTD (KR) 2026-04-02 US claimed
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI ADVANCED MAT CO LTD (KR) 2026-03-05 US claimed
EP-4553121-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI Advanced Materials Co., Ltd. (KR) 2025-05-14 EP claimed
US-20250075100-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI ADVANCED MATERIALS CO., LTD. (KR) 2025-03-06 US claimed
EP-4516836-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI Advanced Materials Co., Ltd. (KR) 2025-03-05 EP claimed
EP-4516837-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF PI Advanced Materials Co., Ltd. (KR) 2025-03-05 EP claimed
US-20250002753-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREFROM PI ADVANCED MATERIALS CO., LTD. (KR) 2025-01-02 US claimed
EP-4484466-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREFROM PI Advanced Materials Co., Ltd. (KR) 2025-01-01 EP claimed
US-20240352315-A1 METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-10-24 US claimed
US-5282941-A Capillary gel electrophoresis columns and method of preparing the same HEWLETT-PACKARD COMPANY (US) 1994-02-01 US claimed
EP-0490406-A2 Capillary gel electrophoresis columns and methods of preparing the same Hewlett-Packard Company (US) 1992-06-17 EP claimed
US-5112460-A High performance microcapillary gel electrophoresis NORTHEASTERN UNIVERSITY (US) 1992-05-12 US claimed
EP-0417925-A2 High performance microcapillary gel electrophoresis NORTHEASTERN UNIVERSITY (US) 1991-03-20 EP claimed
US-4997537-A Silica, coupler NORTHEASTERN UNIVERSITY (US) 1991-03-05 US claimed
EP-0224795-B1 REMOVABLE PRESSURE SENSITIVE ADHESIVE National Starch and Chemical Corporation (US) 1990-03-21 EP claimed
US-4865707-A Capillary gel electrophoresis columns NORTHEASTERN UNIVERSITY (US) 1989-09-12 US claimed
US-4865706-A High performance microcapillary gel electrophoresis NORTHEASTERN UNIVERSITY (US) 1989-09-12 US claimed
EP-0324539-A2 Improved capillary gel electrophoresis columns NORTHEASTERN UNIVERSITY (US) 1989-07-19 EP claimed
US-4716194-A SMALL AMOUNT OF SILANE MONOMER NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1987-12-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092194-A1 POLYIMIDE VARNISH WITH IMPROVED PULSE ENDURANCE AND POLYIMIDE COATING MATERIAL PREPARED THEREOF SMURF1, TET1, VCL TSHR 2046/4885THRB 1196/4885POLB 1316/4885
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME AOC1, AOC2, DDT TSHR 2535/4885THRB 2605/4885POLB 1405/4885
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM CDH1, PBRM1, ITGA1 TSHR 3634/4885THRB 3858/4885POLB 2710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.