Sugi Predict

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Glutamine

Glutamine

SCHEMBL1403799

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nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ PMP22 Q01453 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ GRIK1 P39086 4/20 0.40
▸ GRIA4 P48058 4/20 0.40
▸ GRIK3 Q13003 4/20 0.40
▸ GRIK5 Q16478 4/20 0.40
▸ SLC1A1 P43005 3/20 0.40
▸ GRIA2 P42262 3/20 0.40
▸ SLC1A3 P43003 2/20 0.40
▸ SLC1A2 P43004 2/20 0.40
▸ GRIA1 P42261 2/20 0.40
▸ GRIK2 Q13002 2/20 0.40
▸ GRM8 O00222 1/20 0.40
▸ GRM6 O15303 1/20 0.40
▸ GRIN2D O15399 1/20 0.40
▸ GRIN3B O60391 1/20 0.40
▸ GSR P00390 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL1403796 1.00 ALOX15 (0.54) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL22501364 0.94 KMT2A (0.61) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL6130109 0.94 ALOX15 (0.61) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL9716100 0.91 KMT2A (0.58) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL9716093 0.91 KMT2A (0.58) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8695366 0.91 PDCD1LG2 (0.44) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8695387 0.91 PDCD1LG2 (0.44) ALOX15BLMPMP22KMT2AGRIK1
D-Glutamate SCHEMBL27467695 0.89 GRM8 (0.46) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL14966644 0.89 ALOX15 (0.43) ALOX15BLMPMP22KMT2AGRIK1
Glutamine SCHEMBL6374300 0.89 KMT2A (0.54) ALOX15BLMPMP22KMT2AGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2988772-A1 COMPLEX CSL Ltd. (AU) 2016-03-02 — — EP disclosed
EP-2814502-A1 VON WILLEBRAND FACTOR VARIANTS HAVING IMPROVED FACTOR VIII BINDING AFFINITY CSL Behring GmbH (DE) 2014-12-24 — — EP disclosed
WO-2014173873-A1 COMPLEX CSL BEHRING GMBH (DE) 2014-10-30 — — WO disclosed
WO-2013120939-A1 VON WILLEBRAND FACTOR VARIANTS HAVING IMPROVED FACTOR VIII BINDING AFFINITY CSL BEHRING GMBH (DE) 2013-08-22 — — WO disclosed
EP-2291523-A1 FACTOR VIII, VON WILLEBRAND FACTOR OR COMPLEXES THEREOF WITH PROLONGED IN VIVO HALF-LIFE CSL Behring GmbH (DE) 2011-03-09 — — EP disclosed
WO-2009156137-A1 FACTOR VIII, VON WILLEBRAND FACTOR OR COMPLEXES THEREOF WITH PROLONGED IN VIVO HALF-LIFE CSL BEHRING GMBH (DE) 2009-12-30 — — WO disclosed
EP-1891107-A2 COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES ZymoGenetics, Inc. (US) 2008-02-27 — — EP disclosed
EP-1781782-A1 MODIFIED VITAMIN K DEPENDENT POLYPEPTIDES ZLB Behring GmbH (DE) 2007-05-09 — — EP disclosed
WO-2006124667-A2 COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES ZYMOGENETICS, INC. (US) 2006-11-23 — — WO disclosed
WO-2006018204-A1 MODIFIED VITAMIN K DEPENDENT POLYPEPTIDES ZLB BEHRING GMBH (DE) 2006-02-23 — — WO disclosed
EP-1305408-A2 CELL-WALL DEGRADING ENZYME VARIANTS Novozymes A/S (DK) 2003-05-02 — — EP disclosed
WO-2002006442-A2 CELL-WALL DEGRADING ENZYME VARIANTS NOVOZYMES A/S (DK) 2002-01-24 — — WO disclosed
US-5973119-A NOVEL GENES ENCODING PROTEINS THAT ARE MEMBERS OF THE CELL CYCLE PROTEIN FAMILY KNOWN AS ?CYCLINS?. AMGEN INC. (US) 1999-10-26 — — US disclosed
US-5962636-A AMINO ACID SEQUENCES OF PEPTIDES CAPABLE OF INDUCING INFLAMMATORY CARDIOMYOPATHY IN VIVO; ANTIINFLAMMATORY AGENTS AMGEN CANADA INC. (CA) 1999-10-05 — — US disclosed