Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL8695387 | 1.00 | PDCD1LG2 (0.44) | PDCD1LG2CD274SLC7A5SLC1A1SLC1A3 | |
| Asparagine SCHEMBL27468642 | 0.94 | CD274 (0.40) | PDCD1LG2CD274SLC7A5SLC1A1SLC1A3 | |
| Leucine SCHEMBL8995763 | 0.94 | SLC7A5 (0.55) | PDCD1LG2CD274SLC7A5SLC1A1SLC1A3 | |
| Asparagine SCHEMBL7763890 | 0.93 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Asparagine SCHEMBL1964053 | 0.93 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Asparagine SCHEMBL1964050 | 0.93 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Asparagine SCHEMBL9695773 | 0.93 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Glutamine SCHEMBL1403799 | 0.91 | ALOX15 (0.54) | PDCD1LG2CD274SLC7A5SLC1A1SLC1A3 | |
| Glutamine SCHEMBL1403796 | 0.91 | ALOX15 (0.54) | PDCD1LG2CD274SLC7A5SLC1A1SLC1A3 | |
| Threonine SCHEMBL103941 | 0.89 | USP2 (0.47) | SLC7A5SLC1A1SLC1A3SLC1A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803292-A | Control of protein glycosylation and compositions and methods related thereto | PFIZER | 2012-11-28 | — | — | CN | claimed |
| CN-102803292-A | Control of protein glycosylation and compositions and methods related thereto | PFIZER | 2012-11-28 | — | — | CN | disclosed |
| US-5762921-A | PREVENTING THE COMPLEXING OF A THROMBIN AND THROMBOMODULIN | GENENTECH, INC. (US) | 1998-06-09 | — | — | US | disclosed |