Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13170734 | 0.94 | NPC1 (0.61) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL5679409 | 0.87 | NPC1 (0.56) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL12796879 | 0.87 | NPC1 (0.56) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL25607235 | 0.83 | NPC1 (0.83) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL15604178 | 0.83 | NPC1 (0.83) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL14038080 | 0.82 | ACHE (0.68) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL9571496 | 0.82 | ACHE (0.68) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL11932608 | 0.82 | ACHE (0.68) | PTGS1PTGS2ALOX5NPC1MTOR | |
| SCHEMBL1824534 | 0.81 | BACE1 (0.53) | PTGS1ALOX5NPC1MTORAPP | |
| SCHEMBL1824537 | 0.81 | BACE1 (0.53) | PTGS1ALOX5NPC1MTORAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144065-A1 | OPHTHALMIC FORMULATIONS OF AMYLOID- CONTRAST AGENTS AND METHODS OF USE THEREOF | NEUROPTIX CORPORATION (US) | 2008-11-27 | — | — | WO | disclosed |