Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | NQO2 | P16083 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12796879 | 1.00 | NPC1 (0.56) | NPC1MTORAPPMAPTKDM4E | |
| SCHEMBL13170734 | 0.92 | NPC1 (0.61) | NPC1MTORAPPMAPTKDM4E | |
| SCHEMBL13993018 | 0.89 | TTR (0.56) | NPC1MTORAPPMAPTKDM4E | |
| SCHEMBL14038003 | 0.87 | PTGS1 (0.59) | NPC1MTORAPPMAPTKDM4E | |
| SCHEMBL9856474 | 0.86 | CYP1A1 (0.62) | NPC1APPMAPTKDM4EMEN1 | |
| SCHEMBL1824537 | 0.85 | BACE1 (0.53) | NPC1MTORAPPMAPTKDM4E | |
| SCHEMBL1824534 | 0.85 | BACE1 (0.53) | NPC1MTORAPPMAPTKDM4E | |
| SCHEMBL22887367 | 0.85 | RARA (0.57) | NPC1MTORAPPMAPTTTR | |
| SCHEMBL7942064 | 0.85 | TTR (0.60) | TTRCYP1A1ALOX5PTGS1CYP1B1 | |
| SCHEMBL7942066 | 0.85 | TTR (0.60) | TTRCYP1A1ALOX5PTGS1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197936-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | Hexion Research Belgium SA (BE) | 2017-08-02 | — | — | EP | claimed |
| WO-2016049192-A1 | SILANE FUNCTIONALIZED COMPOUNDS AND COMPOSITIONS THEREOF | HEXION INC. (US) | 2016-03-31 | — | — | WO | claimed |
| EP-1617242-A1 | Process for producing a composition, comprising nano particles | DSM IP Assets B.V. (NL) | 2006-01-18 | — | — | EP | disclosed |
| EP-1016659-B1 | Bismaleimides comprising mesogenic groups and oligomeric liquid crystalline bismaleimides | DAINIPPON INK & CHEMICALS (JP) | 2003-09-24 | — | — | EP | disclosed |
| EP-1281728-A1 | Flexible films having barrier properties | DSM N.V. (NL) | 2003-02-05 | — | — | EP | disclosed |
| US-6169186-B1 | LIQUID CRYSTALS AND LIQUID CRYSTALLINE POLYMERS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-1016659-A1 | Bismaleimides comprising mesogenic groups and oligomeric liquid crystalline bismaleimides | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-0927149-A1 | PROCESS FOR PREPARING AND RECOVERING 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE OR 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENE | THE DOW CHEMICAL COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011044-A1 | PROCESS FOR PREPARING AND RECOVERING 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE OR 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENE | THE DOW CHEMICAL COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| US-5078910-A | Polyacrylates, polyepoxides, low temperature polymerization, potting compounds, composites | EDISON POLYMER INNOVATION CORP. (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0405713-A1 | Polymerization of liquid crystalline monomers | EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) | 1991-01-02 | — | — | EP | disclosed |