Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.48 |
| ▸ | NNMT | P40261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704024 | 1.00 | ACHE (0.57) | ACHEPLAUMKNK1MKNK2ALDH1A1 | |
| SCHEMBL2190365 | 0.86 | ACHE (0.59) | ACHEALDH1A1NNMTCYP3A4MAPK8 | |
| SCHEMBL365917 | 0.82 | ALDH1A1 (0.65) | ACHEPLAUALDH1A1IDO1TDO2 | |
| SCHEMBL2064454 | 0.82 | HTT (0.59) | ACHEPLAUALDH1A1CYP3A4IDO1 | |
| SCHEMBL28623246 | 0.81 | ACHE (0.48) | ACHEPLAUALDH1A1CYP3A4IDO1 | |
| SCHEMBL8115082 | 0.81 | PLAU (0.53) | ACHEPLAUALDH1A1MEN1KMT2A | |
| SCHEMBL1354320 | 0.81 | ALDH1A1 (0.73) | MKNK1MKNK2ALDH1A1PARP15PARP10 | |
| SCHEMBL3787323 | 0.81 | MAPK1 (0.60) | MKNK1MKNK2ALDH1A1PARP15PARP10 | |
| SCHEMBL1034025 | 0.81 | ALDH1A1 (0.68) | ALDH1A1PARP15PARP10KMT2AHPGD | |
| SCHEMBL4115468 | 0.81 | MAOB (0.55) | MKNK1MKNK2ALDH1A1PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562170-A1 | Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-oxo-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-02-27 | — | — | EP | disclosed |
| EP-1988085-A1 | PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-11-05 | — | — | EP | disclosed |