Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572398 | 0.88 | PIK3R1 (0.38) | GPR119FAAHPIK3R1PIK3CA | |
| SCHEMBL14038357 | 0.86 | TP53 (0.41) | GPR119FAAH | |
| SCHEMBL1449700 | 0.82 | PIK3R1 (0.41) | GPR119FAAHPIK3R1PIK3CA | |
| SCHEMBL4572374 | 0.80 | GPR119 (0.38) | GPR119 | |
| SCHEMBL11913110 | 0.78 | GPR119 (0.51) | GPR119 | |
| SCHEMBL11913108 | 0.78 | GPR119 (0.59) | GPR119 | |
| SCHEMBL11913121 | 0.78 | GPR119 (0.49) | GPR119 | |
| SCHEMBL11913118 | 0.77 | GPR119 (0.41) | GPR119 | |
| SCHEMBL11913122 | 0.77 | GPR119 (0.40) | GPR119 | |
| SCHEMBL3706465 | 0.77 | GPR119 (0.43) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137435-A1 | [6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-13 | — | — | WO | disclosed |