Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140989 | 0.88 | — | — | |
| SCHEMBL9912348 | 0.87 | DOT1L (0.30) | DOT1L | |
| SCHEMBL11924463 | 0.87 | DOT1L (0.30) | DOT1L | |
| SCHEMBL12305478 | 0.86 | — | — | |
| SCHEMBL14140990 | 0.77 | — | — | |
| SCHEMBL13532237 | 0.76 | — | — | |
| SCHEMBL15682803 | 0.74 | POLRMT (0.39) | POLRMT | |
| SCHEMBL16710421 | 0.74 | POLRMT (0.36) | POLRMTDOT1L | |
| SCHEMBL12306914 | 0.73 | — | — | |
| SCHEMBL9912351 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141079-A1 | TETRAHYDROFURO [3 4-D] DIOXOLANE COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS AND CANCER | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |