⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306914 | 0.87 | — | — | |
| SCHEMBL14038378 | 0.86 | POLRMT (0.31) | — | |
| SCHEMBL14140989 | 0.78 | — | — | |
| SCHEMBL13392125 | 0.76 | — | — | |
| SCHEMBL11924463 | 0.73 | DOT1L (0.30) | — | |
| SCHEMBL13648870 | 0.71 | — | — | |
| SCHEMBL13532213 | 0.71 | PIK3CD (0.34) | — | |
| SCHEMBL10100148 | 0.71 | — | — | |
| SCHEMBL12306916 | 0.71 | PRMT5 (0.33) | — | |
| SCHEMBL18520959 | 0.70 | GJB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012941-B2 | Carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2011-09-06 | — | — | US | disclosed |
| US-20090317361-A1 | CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2009-12-24 | — | — | US | disclosed |