Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 18/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448511 | 0.82 | BDKRB2 (0.40) | BDKRB2 | |
| SCHEMBL13448488 | 0.81 | BDKRB2 (0.39) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL13448481 | 0.80 | BDKRB2 (0.38) | BDKRB2CYP3A4 | |
| SCHEMBL13146232 | 0.79 | BDKRB2 (0.47) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711428 | 0.78 | BDKRB2 (0.44) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL12711410 | 0.78 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL13093256 | 0.77 | BDKRB2 (0.38) | BDKRB2RORC | |
| SCHEMBL13092954 | 0.77 | BDKRB2 (0.39) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL13448485 | 0.77 | BDKRB2 (0.52) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL13448514 | 0.76 | BDKRB2 (0.41) | BDKRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116620-A1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2008-10-02 | — | — | WO | disclosed |