Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038865 | 0.85 | PARP1 (0.38) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL4708933 | 0.85 | KDM4E (0.43) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL4709065 | 0.84 | PLAT (0.44) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL14257687 | 0.80 | HPGD (0.41) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL14013820 | 0.78 | RAB9A (0.41) | ALDH1A1HPGDPARP1NPC1RAB9A | |
| SCHEMBL4707644 | 0.77 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL4708363 | 0.75 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL14015123 | 0.75 | HPGD (0.37) | L3MBTL1ALDH1A1HPGDGLANPSR1 | |
| SCHEMBL14015115 | 0.73 | ALDH1A1 (0.38) | ALDH1A1HPGDCNR2 | |
| SCHEMBL14015116 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449488-B2 | Pyrazolopyrimidines as protein kinase inhibitors | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |